Reliability and reproducibility issues in DNA microarray measurements

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Reliability and reproducibility issues in DNA microarray measurements.

DNA microarrays enable researchers to monitor the expression of thousands of genes simultaneously. However, the current technology has several limitations. Here we discuss problems related to the sensitivity, accuracy, specificity and reproducibility of microarray results. The existing data suggest that for relatively abundant transcripts the existence and direction (but not the magnitude) of e...

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c 2016 The Korean Society of Neurogastroenterology and Motility J Neurogastroenterol Motil, Vol. 22 No. 3 July, 2016 www.jnmjournal.org TO THE EDITOR: I was interested to read the paper by Suarez AL and colleagues published in the Mar 2016 issue of Journal of Neurogastroenterology and Motility. They aimed to evaluate the reproducibility of sphincter of Oddi manometry. The authors used 214 subje...

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ژورنال

عنوان ژورنال: Trends in Genetics

سال: 2006

ISSN: 0168-9525

DOI: 10.1016/j.tig.2005.12.005